Zinc Sulphate Injection
DEFINITION
Zinc Sulfate Injection is a sterile solution of Zinc Sulfate Heptahydrate in Water for Injections.
The injection complies with the requirements stated under Parenteral Preparations and with the following requirements.
Content of zinc sulfate heptahydrate, ZnSO4,7H2O
95.0 to 105.0% of the stated amount.
IDENTIFICATION
A. A volume of the injection containing 0.1 g of Zinc Sulfate Heptahydrate yields the reaction characteristic of zinc and zinc salts, Appendix VI.
B. A volume of the injection containing 45 mg of Zinc Sulfate Heptahydrate yields the reactions characteristic of sulfates, Appendix VI.
ASSAY
To a volume of the injection containing 0.16 g of Zinc Sulfate Heptahydrate add 5 mL of dilute acetic acid. Carry out the complexemetric titration of zinc, Appendix VIII D.
Each mL of 0.1M sodium edetate is equivalent to 28.75 mg of ZnSO4,7H2O.
