Edition: BP 2025 (Ph. Eur. 11.6 update)<\/p>\n
NOTE: This monograph has been developed to cover unlicensed formulations.<\/p>\n
Action and use<\/strong><\/p>\n Phosphate binder; treatment of hyperphosphataemia.<\/p>\n Calcium Carbonate Oral Suspension is a suspension of Calcium Carbonate in a suitable vehicle.<\/p>\n The oral suspension complies with the requirements stated under Oral Liquids and with the following requirements. Where appropriate, the oral suspension also complies with the requirements stated under Unlicensed Medicines.<\/p>\n Content of calcium carbonate, CaCO3<\/sub><\/strong><\/p>\n 90.0 to 110.0% of the stated amount.<\/p>\n It may be necessary to add a drop of a suitable antifoaming agent to a volume of the oral suspension before carrying out the following tests.<\/p>\n A. Mix 1 volume of the oral suspension with 1 volume of water and filter. The filtrate yields reaction C characteristic of calcium salts, Appendix VI.<\/p>\n B. Dilute a volume of the oral suspension containing 0.6 g of Calcium Carbonate to 2 volumes with 2M hydrochloric acid. The resulting solution yields reaction A characteristic of carbonates, Appendix VI.<\/p>\n pH 7.0 to 8.7, Appendix V L.<\/p>\n Complies with the requirements stated under Unlicensed Medicines, Oral Suspensions. Use a volume of the oral suspension containing one dose.<\/p>\n It may be necessary to add one or two drops of a suitable antifoaming agent to the oral suspension before carrying out the Assay.<\/p>\n To a weighed quantity of the oral suspension containing 0.15 g of Calcium Carbonate add 3 mL of dilute hydrochloric acid and 20 mL of water. Boil for 2 minutes, allow to cool and dilute to 50 mL with water. Carry out the complexometric titration of calcium, Appendix VIII D. Determine the weight per ml of the oral suspension, Appendix V G, and calculate the content of CaCO3<\/sub>, weight in volume.<\/p>\n Each mL of 0.1M sodium edetate is equivalent to 10.01 mg of CaCO3<\/sub>.<\/p>\n","protected":false},"excerpt":{"rendered":" Edition: BP 2025 (Ph. Eur. 11.6 update) NOTE: This monograph has been developed to cover unlicensed formulations. Action and use Phosphate binder; treatment of hyperphosphataemia. DEFINITION Calcium Carbonate Oral Suspension is a suspension of Calcium Carbonate in a suitable vehicle. The oral suspension complies with the requirements stated under Oral Liquids and with the following…<\/p>\n","protected":false},"author":5,"featured_media":7165,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[175],"tags":[],"class_list":["post-7148","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-formulated-preparations-specific-monographs"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/7148","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=7148"}],"version-history":[{"count":2,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/7148\/revisions"}],"predecessor-version":[{"id":7180,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/7148\/revisions\/7180"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/7165"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=7148"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=7148"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=7148"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}DEFINITION<\/h2>\n
IDENTIFICATION<\/h2>\n
TESTS<\/h2>\n
Acidity or alkalinity<\/h3>\n
Dissolution<\/h3>\n
ASSAY<\/h2>\n