{"id":30880,"date":"2025-11-12T16:04:33","date_gmt":"2025-11-12T09:04:33","guid":{"rendered":"https:\/\/nhathuocngocanh.com\/bp\/?p=30880"},"modified":"2025-11-12T16:04:33","modified_gmt":"2025-11-12T09:04:33","slug":"strong-glutaraldehyde-solution","status":"publish","type":"post","link":"https:\/\/nhathuocngocanh.com\/bp\/strong-glutaraldehyde-solution\/","title":{"rendered":"Strong Glutaraldehyde Solution"},"content":{"rendered":"<p>C<sub>5<\/sub>H<sub>8<\/sub>O<sub>2<\/sub>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0100.1 (anhydrous)\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 111-30-8<\/p>\n<p><strong>Action and use<\/strong><\/p>\n<p>Used in treatment of warts.<\/p>\n<p><strong>Preparation<\/strong><\/p>\n<p>Glutaraldehyde Solution<\/p>\n<h2>DEFINITION<\/h2>\n<p>Strong Glutaraldehyde Solution is an aqueous solution of glutaraldehyde (pentanedial). It contains not less than 47.0% and not more than 53.0% w\/w of glutaraldehyde, C<sub>5<\/sub>H<sub>8<\/sub>O<sub>2<\/sub>.<\/p>\n<h2>CHARACTERISTICS<\/h2>\n<p>A colourless or almost colourless solution.<\/p>\n<h2>IDENTIFICATION<\/h2>\n<p>A. Heat 1 mL with 10 mL of a solution containing 1 g of hydroxylamine hydrochloride and 2 g of sodium acetate in water on a water bath for 10 minutes, allow to cool and filter. The melting point of the residue, after washing with water and drying at 105\u00b0, is about 178\u00b0, Appendix V A.<\/p>\n<p>B. Add 0.05 mL to 2 mL of ammoniacal silver nitrate solution and mix gently for a few minutes. Silver is deposited.<\/p>\n<h2>TESTS<\/h2>\n<h3>Acidity<\/h3>\n<p>Dilute 10 mL with 10 mL of carbon dioxide-free water and titrate with 0.1M sodium hydroxide VS using bromothymol blue solution R3 as indicator. Not more than 5.0 mL of 0.1M sodium hydroxide VS is required to change the colour of the solution.<\/p>\n<h3>Clarity and colour of solution<\/h3>\n<p>Dilute 1 volume with 4 volumes of water. The resulting solution is clear, Appendix IV A, and not more intensely coloured than reference solution B6, Appendix IV B, Method I.<\/p>\n<h3>Weight per mL<\/h3>\n<p>1.126 to 1.134 g, Appendix V G.<\/p>\n<h2>ASSAY<\/h2>\n<p>Dissolve 4 g in 100 mL of a 7% w\/v solution of hydroxylamine hydrochloride previously neutralised to bromophenol blue solution with 1M sodium hydroxide VS and allow to stand for 30 minutes. Add 20 mL of petroleum spirit (boiling range, 40\u00b0 to 60\u00b0) and titrate with 1M sodium hydroxide VS until the colour of the aqueous phase matches that of a 7% w\/v solution of hydroxylamine hydrochloride previously neutralised to bromophenol blue solution with 1M sodium hydroxide VS. Each mL of 1M sodium hydroxide VS is equivalent to 50.05 mg of C<sub>5<\/sub>H<sub>8<\/sub>O<sub>2<\/sub>.<\/p>\n<h2>STORAGE<\/h2>\n<p>Strong Glutaraldehyde Solution should be stored at a temperature not exceeding 15\u00b0.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>C5H8O2\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0100.1 (anhydrous)\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 111-30-8 Action and use Used in treatment of warts. Preparation Glutaraldehyde Solution DEFINITION Strong Glutaraldehyde Solution is an aqueous solution of glutaraldehyde (pentanedial). It contains not less than 47.0% and not more than 53.0% w\/w of glutaraldehyde, C5H8O2. CHARACTERISTICS A&#8230;<\/p>\n","protected":false},"author":2,"featured_media":30893,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[174],"tags":[],"class_list":["post-30880","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicinal-substances"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/30880","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=30880"}],"version-history":[{"count":2,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/30880\/revisions"}],"predecessor-version":[{"id":30895,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/30880\/revisions\/30895"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/30893"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=30880"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=30880"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=30880"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}