{"id":30036,"date":"2025-11-11T14:42:26","date_gmt":"2025-11-11T07:42:26","guid":{"rendered":"https:\/\/nhathuocngocanh.com\/bp\/?p=30036"},"modified":"2025-11-11T14:42:26","modified_gmt":"2025-11-11T07:42:26","slug":"sodium-carbonate","status":"publish","type":"post","link":"https:\/\/nhathuocngocanh.com\/bp\/sodium-carbonate\/","title":{"rendered":"Sodium Carbonate"},"content":{"rendered":"

Anhydrous Sodium Carbonate<\/p>\n

(Ph. Eur. monograph 0773)<\/p>\n

Na2<\/sub>CO3<\/sub>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0106.0\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 497-19-8<\/p>\n

DEFINITION<\/h2>\n

Content<\/h3>\n

99.5 per cent to 100.5 per cent (dried substance).<\/p>\n

CHARACTERS<\/h2>\n

Appearance<\/h3>\n

White or almost white, slightly granular powder, hygroscopic.<\/p>\n

Solubility<\/h3>\n

Freely soluble in water, practically insoluble in ethanol (96 per cent).<\/p>\n

IDENTIFICATION<\/h2>\n

A. Dissolve 1 g in water R and dilute to 10 mL with the same solvent. The solution is strongly alkaline (2.2.4).<\/p>\n

B. The solution prepared for identification test A gives the reaction of carbonates (2.3.1).<\/p>\n

C. The solution prepared for identification test A gives reaction (a) of sodium (2.3.1).<\/p>\n

D. Loss on drying (see Tests).<\/p>\n

TESTS<\/h2>\n

Solution S<\/h3>\n

Dissolve 2.0 g in portions in a mixture of 5 mL of hydrochloric acid R and 25 mL of distilled water R. Heat to boiling and cool. Add dilute sodium hydroxide solution R until the solution is neutral and dilute to 50 mL with distilled water R.<\/p>\n

Appearance of solution<\/h3>\n

The solution is clear (2.2.1) and not more intensely coloured than reference solution Y6<\/sub> (2.2.2, Method I).<\/p>\n

Dissolve 2.0 g in 10 mL of water R.<\/p>\n

Alkali hydroxides and bicarbonates<\/h3>\n

Dissolve 0.4 g in 20 mL of water R. Add 20 mL of barium chloride solution R1 and filter. To 10 mL of the filtrate add 0.1 mL of phenolphthalein solution R. The solution does not become red. Boil the remainder of the filtrate for 2 min. The solution
\nremains clear (2.2.1).<\/p>\n

Chlorides (2.4.4)<\/h3>\n

Maximum 125 ppm.<\/p>\n

Dissolve 0.4 g in water R, add 4 mL of dilute nitric acid R and dilute to 15 mL with water R.<\/p>\n

Sulfates (2.4.13)<\/h3>\n

Maximum 250 ppm, determined on solution S.<\/p>\n

Iron (2.4.9)<\/h3>\n

Maximum 50 ppm.<\/p>\n

Dilute 5 mL of solution S to 10 mL with water R.<\/p>\n

Loss on drying (2.2.32)<\/h4>\n

Maximum 1.0 per cent, determined on 1.000 g by drying in an oven at 300 \u00b1 15 \u00b0C.<\/p>\n

ASSAY<\/h2>\n

Dissolve 0.400 g in 50 mL of carbon dioxide-free water R. Titrate with 1 M hydrochloric acid, determining the end-point potentiometrically (2.2.20). Read the volume added at the 2 point of inflection.<\/p>\n

1 mL of 1 M hydrochloric acid is equivalent to 52.99 mg of Na2<\/sub>CO3<\/sub>.<\/p>\n

STORAGE<\/h2>\n

In an airtight container.<\/p>\n","protected":false},"excerpt":{"rendered":"

Anhydrous Sodium Carbonate (Ph. Eur. monograph 0773) Na2CO3\u00a0 \u00a0 \u00a0 \u00a0 \u00a0106.0\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 497-19-8 DEFINITION Content 99.5 per cent to 100.5 per cent (dried substance). CHARACTERS Appearance White or almost white, slightly granular powder, hygroscopic. Solubility Freely soluble in water, practically insoluble in ethanol (96 per cent). IDENTIFICATION A. Dissolve 1 g…<\/p>\n","protected":false},"author":2,"featured_media":30047,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[174],"tags":[],"class_list":["post-30036","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicinal-substances"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/30036","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=30036"}],"version-history":[{"count":2,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/30036\/revisions"}],"predecessor-version":[{"id":30049,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/30036\/revisions\/30049"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/30047"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=30036"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=30036"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=30036"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}