{"id":29400,"date":"2025-11-10T16:25:38","date_gmt":"2025-11-10T09:25:38","guid":{"rendered":"https:\/\/nhathuocngocanh.com\/bp\/?p=29400"},"modified":"2025-11-10T16:25:38","modified_gmt":"2025-11-10T09:25:38","slug":"refined-safflower-oil","status":"publish","type":"post","link":"https:\/\/nhathuocngocanh.com\/bp\/refined-safflower-oil\/","title":{"rendered":"Refined Safflower Oil"},"content":{"rendered":"

Edition: BP 2025 (Ph. Eur. 11.6 update)<\/p>\n

DEFINITION<\/h2>\n

Fatty oil obtained from seeds of Carthamus tinctorius L. (type I) or from seeds of hybrids of Carthamus tinctorius L. (type II), by expression and\/or extraction followed by refining. Type II refined safflower oil is rich in oleic ((9Z)-octadec-9- enoic) acid. A suitable antioxidant may be added.<\/p>\n

PRODUCTION<\/h2>\n

The oil is prepared using materials and methods designed to ensure that the content of brassicasterol (2.4.23) in the sterol fraction of the oil is not greater than 0.3 per cent.<\/p>\n

CHARACTERS<\/h2>\n

Appearance<\/h3>\n

Clear, viscous, yellow or pale yellow liquid.<\/p>\n

Solubility<\/h3>\n

Practically insoluble in ethanol (96 per cent), miscible with light petroleum (bp: 40-60 \u00b0C).<\/p>\n\n\n\n\n\n
<\/td>\nType I refined safflower oil<\/strong><\/td>\nType II refined safflower oil<\/strong><\/td>\n<\/tr>\n
Relative density<\/td>\nabout 0.922<\/td>\nabout 0.914<\/td>\n<\/tr>\n
Refractive index<\/td>\nabout 1.476<\/td>\nabout 1.472<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

IDENTIFICATION<\/h2>\n

First identification: B.<\/em><\/p>\n

Second identification: A.<\/em><\/p>\n

A. Identification of fatty oils by thin-layer chromatography (2.3.2).<\/p>\n

Results The chromatogram obtained is similar to the corresponding chromatogram for type I or type II shown in Figure 2.3.2.-1.<\/p>\n

B. Composition of fatty acids (see Tests).<\/p>\n

TESTS<\/h2>\n

Acid value (2.5.1)<\/h3>\n

Maximum 0.5.<\/p>\n

Peroxide value (2.5.5, Method A)<\/h3>\n

Maximum 10.0, or maximum 5.0 if intended for use in the manufacture of parenteral preparations.<\/p>\n

Unsaponifiable matter (2.5.7)<\/h3>\n

Maximum 1.5 per cent, determined on 5.0 g.<\/p>\n

Alkaline impurities (2.4.19)<\/h3>\n

It complies with the test.<\/p>\n

Composition of fatty acids (2.4.22, Method A)<\/h3>\n

Use the mixture of calibrating substances in Table 2.4.22.-3.<\/p>\n

Composition of the fatty-acid fraction of type I refined safflower oil:<\/p>\n

\u2014 saturated fatty acids of chain length less than C14: maximum 0.2 per cent;<\/p>\n

\u2014 myristic acid: maximum 0.2 per cent;<\/p>\n

\u2014 palmitic acid: 4.0 per cent to 10.0 per cent;<\/p>\n

\u2014 stearic acid: 1.0 per cent to 5.0 per cent;<\/p>\n

\u2014 oleic acid: 8.0 per cent to 21.0 per cent;<\/p>\n

\u2014 linoleic acid: 68.0 per cent to 83.0 per cent;<\/p>\n

\u2014 linolenic acid: maximum 0.5 per cent;<\/p>\n

\u2014 arachidic acid: maximum 0.5 per cent;<\/p>\n

\u2014 eicosenoic acid: maximum 0.5 per cent;<\/p>\n

\u2014 behenic acid: maximum 1.0 per cent.<\/p>\n

Composition of the fatty-acid fraction of type II refined safflower oil:<\/p>\n

\u2014 saturated fatty acids of chain length less than C14: maximum 0.2 per cent;<\/p>\n

\u2014 myristic acid: maximum 0.2 per cent;<\/p>\n

\u2014 palmitic acid: 3.6 per cent to 6.0 per cent;<\/p>\n

\u2014 stearic acid: 1.0 per cent to 5.0 per cent;<\/p>\n

\u2014 oleic acid: 70.0 per cent to 84.0 per cent;<\/p>\n

\u2014 linoleic acid: 7.0 per cent to 23.0 per cent;<\/p>\n

\u2014 linolenic acid: maximum 0.5 per cent;<\/p>\n

\u2014 arachidic acid: maximum 1.0 per cent;<\/p>\n

\u2014 eicosenoic acid: maximum 1.0 per cent;<\/p>\n

\u2014 behenic acid: maximum 1.2 per cent.<\/p>\n

Water (2.5.32)<\/h3>\n

Maximum 0.1 per cent, determined on 1.00 g.<\/p>\n

STORAGE<\/h2>\n

In a well-filled, airtight container, protected from light.<\/p>\n

LABELLING<\/h2>\n

The label states:<\/p>\n

\u2014 where applicable, that the substance is suitable for use in the manufacture of parenteral preparations;<\/p>\n

\u2014 the type of oil (type I or type II).<\/p>\n","protected":false},"excerpt":{"rendered":"

Edition: BP 2025 (Ph. Eur. 11.6 update) DEFINITION Fatty oil obtained from seeds of Carthamus tinctorius L. (type I) or from seeds of hybrids of Carthamus tinctorius L. (type II), by expression and\/or extraction followed by refining. Type II refined safflower oil is rich in oleic ((9Z)-octadec-9- enoic) acid. A suitable antioxidant may be added….<\/p>\n","protected":false},"author":5,"featured_media":29401,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[174],"tags":[],"class_list":["post-29400","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicinal-substances"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/29400","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=29400"}],"version-history":[{"count":2,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/29400\/revisions"}],"predecessor-version":[{"id":29409,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/29400\/revisions\/29409"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/29401"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=29400"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=29400"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=29400"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}