﻿{"id":2924,"date":"2025-09-22T17:05:10","date_gmt":"2025-09-22T10:05:10","guid":{"rendered":"https:\/\/nhathuocngocanh.com\/bp\/?p=2924"},"modified":"2025-09-30T16:10:15","modified_gmt":"2025-09-30T09:10:15","slug":"aluminium-acetate-ear-drops","status":"publish","type":"post","link":"https:\/\/nhathuocngocanh.com\/bp\/aluminium-acetate-ear-drops\/","title":{"rendered":"Aluminium Acetate Ear Drops"},"content":{"rendered":"<p>\u200b\u200b\u200b\u200b\u200b\u200b\u200bEdition: BP 2025 (Ph. Eur. 11.6 update)<\/p>\n<p>Aluminium Acetate Ear Drops<\/p>\n<p>General Notices<\/p>\n<h2>DEFINITION<\/h2>\n<table data-start=\"115\" data-end=\"422\">\n<tbody data-start=\"203\" data-end=\"422\">\n<tr data-start=\"203\" data-end=\"246\">\n<td data-start=\"203\" data-end=\"230\" data-col-size=\"sm\">Aluminium Sulfate<\/td>\n<td data-col-size=\"sm\" data-start=\"230\" data-end=\"246\">225 g<\/td>\n<\/tr>\n<tr data-start=\"247\" data-end=\"290\">\n<td data-start=\"247\" data-end=\"274\" data-col-size=\"sm\">Calcium Carbonate<\/td>\n<td data-col-size=\"sm\" data-start=\"274\" data-end=\"290\">100 g<\/td>\n<\/tr>\n<tr data-start=\"291\" data-end=\"334\">\n<td data-start=\"291\" data-end=\"318\" data-col-size=\"sm\">Tartaric Acid<\/td>\n<td data-col-size=\"sm\" data-start=\"318\" data-end=\"334\">45 g<\/td>\n<\/tr>\n<tr data-start=\"335\" data-end=\"378\">\n<td data-start=\"335\" data-end=\"362\" data-col-size=\"sm\">Acetic Acid (33%)<\/td>\n<td data-col-size=\"sm\" data-start=\"362\" data-end=\"378\">250 mL<\/td>\n<\/tr>\n<tr data-start=\"379\" data-end=\"422\">\n<td data-start=\"379\" data-end=\"406\" data-col-size=\"sm\">Purified Water<\/td>\n<td data-col-size=\"sm\" data-start=\"406\" data-end=\"422\">750 mL<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>Extemporaneous preparation<\/strong><\/p>\n<p>The following directions apply.<\/p>\n<p>Dissolve the Aluminium Sulfate in 600 mL of the Purified Water, add the Acetic Acid and then the Calcium Carbonate mixed with the remainder of the Purified Water and allow to stand for not less than 24 hours in a cool place, stirring occasionally. Filter, add the Tartaric Acid to the filtrate and mix.<\/p>\n<p>The ear drops comply with the requirements stated under Ear Preparations and with the following requirements.<\/p>\n<p><strong>Content of aluminium, Al<\/strong><\/p>\n<p>1.7 to 1.9% w\/v.<\/p>\n<h2>CHARACTERISTICS<\/h2>\n<p>A clear liquid.<\/p>\n<p>Weight per mL<\/p>\n<p>1.06 to 1.08 g, Appendix V G.<\/p>\n<h2>ASSAY<\/h2>\n<p>Dilute 10 mL to 100 mL with water. To 10 mL of the resulting solution add 40 mL of 0.05M disodium edetate VS, 90 mL of water and 0.15 mL of methyl red solution. Neutralise by the drop wise addition of 1M sodium hydroxide and warm on a water bath for 30 minutes. Cool, add 1 mL of 2M nitric acid and 5 g of hexamine and titrate with 0.05M lead nitrate VS using 0.5 mL of xylenol orange solution as indicator. Each mL of 0.05M disodium edetate VS is equivalent to 1.349 mg of Al.<\/p>\n<h2>STORAGE<\/h2>\n<p>Aluminium Acetate Ear Drops should be kept in a well-filled container.<\/p>\n<p>When aluminium acetate solution or Burow\u2019s Solution is prescribed or demanded a solution complying with the requirements of this monograph shall be dispensed or supplied.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u200b\u200b\u200b\u200b\u200b\u200b\u200bEdition: BP 2025 (Ph. Eur. 11.6 update) Aluminium Acetate Ear Drops General Notices DEFINITION Aluminium Sulfate 225 g Calcium Carbonate 100 g Tartaric Acid 45 g Acetic Acid (33%) 250 mL Purified Water 750 mL Extemporaneous preparation The following directions apply. Dissolve the Aluminium Sulfate in 600 mL of the Purified Water, add the Acetic&#8230;<\/p>\n","protected":false},"author":5,"featured_media":2925,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[175],"tags":[],"class_list":["post-2924","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-formulated-preparations-specific-monographs"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/2924","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=2924"}],"version-history":[{"count":2,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/2924\/revisions"}],"predecessor-version":[{"id":6557,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/2924\/revisions\/6557"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/2925"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=2924"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=2924"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=2924"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}