﻿{"id":28570,"date":"2025-11-08T15:59:11","date_gmt":"2025-11-08T08:59:11","guid":{"rendered":"https:\/\/nhathuocngocanh.com\/bp\/?p=28570"},"modified":"2025-11-10T16:13:29","modified_gmt":"2025-11-10T09:13:29","slug":"tannic-acid","status":"publish","type":"post","link":"https:\/\/nhathuocngocanh.com\/bp\/tannic-acid\/","title":{"rendered":"Tannic Acid"},"content":{"rendered":"<p>Edition: BP 2025 (Ph. Eur. 11.6 update)<\/p>\n<p><strong>Action and use<\/strong><\/p>\n<p>Astringent.<\/p>\n<h2>DEFINITION<\/h2>\n<p>Mixture of esters of glucose with gallic acid and 3-galloylgallic acid.<\/p>\n<h2>CHARACTERS<\/h2>\n<h3>Appearance<\/h3>\n<p>Yellowish-white or slightly brown amorphous light powder or shiny plates.<\/p>\n<h3>Solubility<\/h3>\n<p>Very soluble in water, freely soluble in acetone, in ethanol (96 per cent) and in glycerol (85 per cent), practically insoluble in methylene chloride.<\/p>\n<h2>IDENTIFICATION<\/h2>\n<p>A. Dilute 0.1 mL of solution S (see Tests) to 5 mL with water R. Add 0.1 mL of ferric chloride solution R1. A blackish-blue colour is produced which becomes green on the addition of 1 mL of dilute sulfuric acid R.<\/p>\n<p>B. To 1 mL of solution S, add 3 mL of a 1 g\/L solution of gelatin R. The mixture becomes turbid and a flocculent precipitate is formed.<\/p>\n<p>C. Dilute 0.1 mL of solution S to 5 mL with water R. Add 0.3 mL of barium hydroxide solution R. A greenish-blue precipitate is formed.<\/p>\n<h2>TESTS<\/h2>\n<h3>Solution S<\/h3>\n<p>Dissolve 4.0 g in carbon dioxide-free water R and dilute to 20 mL with the same solvent.<\/p>\n<h3>Appearance of solution<\/h3>\n<p>Solution S is not more opalescent than reference suspension II (2.2.1).<\/p>\n<h3>Dextrins, gum, salts, sugars<\/h3>\n<p>To 2 mL of solution S, add 2 mL of ethanol (96 per cent) R. The solution is clear. Add 1 mL of ether R. The solution remains clear for at least 10 min.<\/p>\n<h3>Resins<\/h3>\n<p>To 5 mL of solution S, add 5 mL of water R. The mixture remains clear (2.2.1) for at least 15 min.<\/p>\n<p><strong>Loss on drying (2.2.32)<\/strong><\/p>\n<p>Maximum 12.0 per cent, determined on 0.200 g by drying at 105 \u00b0C.<\/p>\n<p><strong>Sulfated ash (2.4.14)<\/strong><\/p>\n<p>Maximum 0.1 per cent, determined on 1.0 g.<\/p>\n<h2>STORAGE<\/h2>\n<p>Protected from light.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Edition: BP 2025 (Ph. Eur. 11.6 update) Action and use Astringent. DEFINITION Mixture of esters of glucose with gallic acid and 3-galloylgallic acid. CHARACTERS Appearance Yellowish-white or slightly brown amorphous light powder or shiny plates. Solubility Very soluble in water, freely soluble in acetone, in ethanol (96 per cent) and in glycerol (85 per cent),&#8230;<\/p>\n","protected":false},"author":5,"featured_media":28571,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[174],"tags":[],"class_list":["post-28570","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicinal-substances"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/28570","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=28570"}],"version-history":[{"count":3,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/28570\/revisions"}],"predecessor-version":[{"id":29369,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/28570\/revisions\/29369"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/28571"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=28570"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=28570"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=28570"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}