Action and use<\/strong><\/p>\n Oxygen supplementation for medical emergencies.<\/p>\n Oxygen produced in a two-stage adsorption plant, applying differential pressures to the adsorption vessels, using different zeolites \/ molecular sieves to reduce the levels of nitrogen and argon in the ambient air.<\/p>\n Minimum 96.0 per cent V\/V of O2, the remainder consists mainly of argon and nitrogen.<\/p>\n This monograph does not apply to gas produced using individual concentrators for domiciliary use.<\/p>\n Colourless gas.<\/p>\n It complies with the limits of the assay.<\/p>\n Maximum 300 ppm V\/V, continuously determined using an infrared analyser (2.5.24).<\/p>\n Gas to be examined: The substance to be examined. It must be filtered to avoid stray light phenomena.<\/p>\n Reference gas (a): A mixture of 2 per cent V\/V of nitrogen R1 and 98 per cent V\/V of oxygen R.<\/p>\n Reference gas (b): A mixture of 2 per cent V\/V of nitrogen R1 and 98 per cent V\/V of oxygen R, containing 300 ppm V\/V of carbon dioxide R1.<\/p>\n Calibrate the apparatus and set the sensitivity using reference gases (a) and (b). Measure the content of carbon dioxide in the gas to be examined.<\/p>\n Maximum 5 ppm V\/V, continuously determined using an infrared analyser (2.5.25).<\/p>\n Gas to be examined: The substance to be examined. It must be filtered to avoid stray light phenomena.<\/p>\n Reference gas (a): A mixture of 2 per cent V\/V of nitrogen R1 and 98 per cent V\/V of oxygen R.<\/p>\n Reference gas (b): A mixture containing 5 ppm V\/V of carbon monoxide R in nitrogen R1.<\/p>\n Calibrate the apparatus and set the sensitivity using reference gases (a) and (b). Measure the content of carbon monoxide in the gas to be examined.<\/p>\n Maximum 2 ppm V\/V in total, determined using a chemiluminescence analyser (2.5.26).<\/p>\n Gas to be examined: The substance to be examined.<\/p>\n Reference gas (a): A mixture of 2 per cent V\/V of nitrogen R1 and 98 per cent V\/V of oxygen R, containing less than 0.05 ppm V\/V of nitrogen monoxide and nitrogen dioxide.<\/p>\n Reference gas (b): A mixture of 2 per cent V\/V of nitrogen R1 and 98 per cent V\/V of oxygen R, containing 2 ppm V\/V of nitrogen dioxide R.<\/p>\n Calibrate the apparatus and set the sensitivity using reference gases (a) and (b). Measure the content of nitrogen monoxide and nitrogen dioxide in the gas to be examined.<\/p>\n Maximum 1 ppm V\/V, determined using an ultraviolet fluorescence analyser (Figure 3098.-1).<\/p>\n Figure 3098.-1. \u2013 UV fluorescence analyser<\/p>\n The apparatus consists of the following:<\/p>\n \u2014 a system generating ultraviolet radiation with a wavelength of 210 nm, made up of an ultraviolet lamp, a collimator, and a selective filter; the beam is blocked periodically by a chopper rotating at high speeds;<\/p>\n \u2014 a reaction chamber, through which flows the gas to be examined;<\/p>\n \u2014 a system that detects radiation emitted at a wavelength of 350 nm, made up of a selective filter, a photomultiplier tube and an amplifier.<\/p>\n Gas to be examined: The substance to be examined. It must be filtered.<\/p>\n Reference gas (a): A mixture of 2 per cent V\/V of nitrogen R1 and 98 per cent V\/V of oxygen R.<\/p>\n Reference gas (b): A mixture of 2 per cent V\/V of nitrogen R1 and 98 per cent V\/V of oxygen R, containing 0.5 ppm V\/V to 2 ppm V\/V of sulfur dioxide R1.<\/p>\n Calibrate the apparatus and set the sensitivity using reference gases (a) and (b). Measure the content of sulfur dioxide in the gas to be examined.<\/p>\n Maximum 0.1 mg\/m3<\/sup> , determined using an oil detector tube (2.1.6).<\/p>\n Maximum 67 ppm V\/V, continuously determined using an electrolytic hygrometer (2.5.28).<\/p>\n A risk assessment must be performed to identify any additional impurities that may be present in the gas produced by the two-stage adsorption plant.<\/p>\n Where applicable, special consideration should be given to identifying any potential impurities that could cause harm to the patient, related to:<\/p>\n \u2014 the environment in which the plant is situated;<\/p>\n \u2014 any emissions within the plant that could lead to impurities;<\/p>\n \u2014 compression of the oxygen when filling high-pressure cylinders.<\/p>\n When indicated by the risk assessment, some or all of these impurities may need to be continuously monitored.<\/p>\n Continuously determine the content of oxygen using a paramagnetic analyser (2.5.27).<\/p>\n Storage requirements are not applicable where Oxygen (98 per cent) is produced by an on-site adsorption plant that feeds the gas directly into a medical gas pipeline system (via buffer vessels) for delivery to the patient.<\/p>\n Where the surplus gas produced is compressed into a high-pressure vessel \/ manifolded cylinders, for use as a reserve supply to cover variability in demand or as a backup supply, it may be stored in suitable containers complying with relevant national pressure equipment regulations. Oils and grease are not to be used unless they are oxygen-compatible.<\/p>\n When the gas produced is stored, the label states the nominal content of O2 in per cent V\/V.<\/p>\n A. CO2<\/sub>: carbon dioxide;<\/p>\n B. CO: carbon monoxide;<\/p>\n C. SO2<\/sub>: sulfur dioxide;<\/p>\n D. NO and NO2: nitrogen monoxide and nitrogen dioxide;<\/p>\n E. oil;<\/p>\n F. H2<\/sub>O: water.<\/p>\n","protected":false},"excerpt":{"rendered":" (Ph. Eur. monograph 3098) O2\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a032.00 Action and use Oxygen supplementation for medical emergencies. DEFINITION Oxygen produced in a two-stage adsorption plant, applying differential pressures to the adsorption vessels, using different zeolites \/ molecular sieves to reduce the levels of nitrogen and argon in the ambient air. Content Minimum 96.0 per…<\/p>\n","protected":false},"author":2,"featured_media":26165,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[174],"tags":[],"class_list":["post-26150","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicinal-substances"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/26150","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=26150"}],"version-history":[{"count":3,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/26150\/revisions"}],"predecessor-version":[{"id":26169,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/26150\/revisions\/26169"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/26165"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=26150"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=26150"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=26150"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}DEFINITION<\/h2>\n
Content<\/h3>\n
CHARACTERS<\/h2>\n
Appearance<\/h3>\n
IDENTIFICATION<\/h2>\n
TESTS<\/h2>\n
Carbon dioxide<\/h3>\n
Carbon monoxide<\/h3>\n
Nitrogen monoxide and nitrogen dioxide<\/h3>\n
Sulfur dioxide<\/h2>\n
![\"Oxygen](\"https:\/\/nhathuocngocanh.com\/bp\/wp-content\/uploads\/2025\/11\/Oxygen-93-per-cent-1-300x163.jpg\")
<\/p>\nOil<\/h3>\n
Water<\/h3>\n
Other impurities<\/h3>\n
ASSAY<\/h2>\n
STORAGE<\/h2>\n
LABELLING<\/h2>\n
IMPURITIES<\/h2>\n