{"id":26122,"date":"2025-11-05T11:15:35","date_gmt":"2025-11-05T04:15:35","guid":{"rendered":"https:\/\/nhathuocngocanh.com\/bp\/?p=26122"},"modified":"2025-11-05T11:15:35","modified_gmt":"2025-11-05T04:15:35","slug":"oxygen","status":"publish","type":"post","link":"https:\/\/nhathuocngocanh.com\/bp\/oxygen\/","title":{"rendered":"Oxygen"},"content":{"rendered":"<p>(Ph. Eur. monograph 0417)<\/p>\n<p>Oxygen should be kept in approved metal cylinders, the shoulders of which are painted white and the remainder black. The cylinder should carry a label stating \u2018Oxygen\u2019. In addition, \u2018Oxygen\u2019 or the symbol \u2018O<sub>2<\/sub>\u2019 should be stencilled in paint on the shoulder of the cylinder.<\/p>\n<p>When Oxygen is intended for use in a room in which magnetic resonance imaging (MRI) is being performed, the cylinder and fittings should be made from suitable non-ferromagnetic materials and labelled accordingly.<\/p>\n<p>O<sub>2<\/sub>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a032.00\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a07782-44-7<\/p>\n<h2>DEFINITION<\/h2>\n<h3>Content<\/h3>\n<p>Minimum 99.5 per cent V\/V of O<sub>2<\/sub>.<\/p>\n<p>This monograph applies to oxygen for medicinal use.<\/p>\n<h2>CHARACTERS<\/h2>\n<h3>Appearance<\/h3>\n<p>Colourless gas.<\/p>\n<h3>Solubility<\/h3>\n<p>At 20 \u00b0C and at a pressure of 101 kPa, 1 volume dissolves in about 32 volumes of water.<\/p>\n<h2>PRODUCTION<\/h2>\n<p>Oxygen is produced by a purification process followed by cryodistillation of the ambient air.<\/p>\n<h3>Carbon dioxide<\/h3>\n<p>Maximum 300 ppm V\/V, determined using an infrared analyser (2.5.24).<\/p>\n<p>Gas to be examined: Filter the substance to be examined to avoid stray light phenomena.<\/p>\n<p>Reference gas (a): Oxygen R.<\/p>\n<p>Reference gas (b): Mixture containing 300 ppm V\/V of carbon dioxide R1 in nitrogen R1.<\/p>\n<p>Calibrate the apparatus and set the sensitivity using reference gases (a) and (b). Measure the content of carbon dioxide in the gas to be examined.<\/p>\n<h3>Carbon monoxide<\/h3>\n<p>Maximum 5 ppm V\/V, determined using an infrared analyser (2.5.25).<\/p>\n<p>Gas to be examined: Filter the substance to be examined to avoid stray light phenomena.<\/p>\n<p>Reference gas (a): Oxygen R.<\/p>\n<p>Reference gas (b): Mixture containing 5 ppm V\/V of carbon monoxide R in nitrogen R1.<\/p>\n<p>Calibrate the apparatus and set the sensitivity using reference gases (a) and (b). Measure the content of carbon monoxide in the gas to be examined.<\/p>\n<h4>Water<\/h4>\n<p>Maximum 67 ppm V\/V, determined using an electrolytic hygrometer (2.5.28).<\/p>\n<h3>Assay<\/h3>\n<p>Determine the concentration of oxygen using a paramagnetic analyser (2.5.27).<\/p>\n<h2>IDENTIFICATION<\/h2>\n<p>It complies with the limits of the assay.<\/p>\n<h2>TESTS<\/h2>\n<h3>Carbon dioxide<\/h3>\n<p>Maximum 300 ppm V\/V, determined using a carbon dioxide detector tube (2.1.6).<\/p>\n<h3>Carbon monoxide<\/h3>\n<p>Maximum 5 ppm V\/V, determined using a carbon monoxide detector tube (2.1.6).<\/p>\n<h3>Water vapour<\/h3>\n<p>Maximum 67 ppm V\/V, determined using a water vapour detector tube (2.1.6).<\/p>\n<h2>STORAGE<\/h2>\n<p>As a compressed gas or liquid in appropriate containers, complying with the legal regulations. Oils and grease are not to be used unless they are oxygen-compatible.<\/p>\n<h2>IMPURITIES<\/h2>\n<p>Specified impurities A, B, C.<\/p>\n<p>A. CO<sub>2<\/sub>: carbon dioxide,<\/p>\n<p>B. CO: carbon monoxide,<\/p>\n<p>C. H<sub>2<\/sub>O: water.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>(Ph. Eur. monograph 0417) Oxygen should be kept in approved metal cylinders, the shoulders of which are painted white and the remainder black. The cylinder should carry a label stating \u2018Oxygen\u2019. In addition, \u2018Oxygen\u2019 or the symbol \u2018O2\u2019 should be stencilled in paint on the shoulder of the cylinder. When Oxygen is intended for use&#8230;<\/p>\n","protected":false},"author":2,"featured_media":26124,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[174],"tags":[],"class_list":["post-26122","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicinal-substances"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/26122","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=26122"}],"version-history":[{"count":2,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/26122\/revisions"}],"predecessor-version":[{"id":26126,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/26122\/revisions\/26126"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/26124"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=26122"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=26122"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=26122"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}