{"id":25966,"date":"2025-11-05T09:35:00","date_gmt":"2025-11-05T02:35:00","guid":{"rendered":"https:\/\/nhathuocngocanh.com\/bp\/?p=25966"},"modified":"2025-11-05T09:35:00","modified_gmt":"2025-11-05T02:35:00","slug":"oleic-acid","status":"publish","type":"post","link":"https:\/\/nhathuocngocanh.com\/bp\/oleic-acid\/","title":{"rendered":"Oleic Acid"},"content":{"rendered":"<p><em>(Ph. Eur. monograph 0799)<\/em><\/p>\n<p>112-80-1<\/p>\n<p><strong>Action and use<\/strong><\/p>\n<p>Excipient.<\/p>\n<h2>DEFINITION<\/h2>\n<p>(Z)-Octadec-9-enoic acid (C<sub>18<\/sub>H<sub>34<\/sub>O<sub>2<\/sub>; M<sub>r<\/sub> 282.5), together with varying amounts of saturated and other unsaturated fatty acids. A suitable antioxidant may be added.<\/p>\n<h3>Content<\/h3>\n<p>65.0 per cent to 88.0 per cent of C<sub>18<\/sub>H<sub>34<\/sub>O<sub>2<\/sub>.<\/p>\n<h2>CHARACTERS<\/h2>\n<h3>Appearance<\/h3>\n<p>Clear, yellowish or brownish, oily liquid.<\/p>\n<h3>Solubility<\/h3>\n<p>Practically insoluble in water, miscible with ethanol (96 per cent) and with methylene chloride.<\/p>\n<h3>Relative density<\/h3>\n<p>About 0.892.<\/p>\n<h2>IDENTIFICATION<\/h2>\n<p>A. Acid value (see Tests).<\/p>\n<p>B. Iodine value (see Tests).<\/p>\n<p>C. Composition of fatty acids (see Tests).<\/p>\n<p>Margaric acid: Maximum 0.2 per cent for oleic acid of vegetable origin and maximum 4.0 per cent for oleic acid of animal origin.<\/p>\n<h2>TESTS<\/h2>\n<h3>Appearance<\/h3>\n<p>The substance to be examined is not more intensely coloured than reference solution Y1 or BY1 (2.2.2,Method I).<\/p>\n<h3>Acid value (2.5.1)<\/h3>\n<p>195 to 204, determined on 0.5 g.<\/p>\n<h3>Iodine value (2.5.4)<\/h3>\n<p>89 to 105.<\/p>\n<h3>Peroxide value (2.5.5)<\/h3>\n<p>Maximum 10.0.<\/p>\n<h3>Composition of fatty acids<\/h3>\n<p>Gas chromatography (2.4.22, Method C).<\/p>\n<p>Test solution: Prepare as described in the method but omitting the initial hydrolysis.<\/p>\n<p>Composition of the fatty acid fraction of the substance:<\/p>\n<p>\u2014 myristic acid: maximum 5.0 per cent,<\/p>\n<p>\u2014 palmitic acid: maximum 16.0 per cent,<\/p>\n<p>\u2014 palmitoleic acid: maximum 8.0 per cent,<\/p>\n<p>\u2014 stearic acid: maximum 6.0 per cent,<\/p>\n<p>\u2014 oleic acid: 65.0 per cent to 88.0 per cent,<\/p>\n<p>\u2014 linoleic acid: maximum 18.0 per cent,<\/p>\n<p>\u2014 linolenic acid: maximum 4.0 per cent,<\/p>\n<p>\u2014 fatty acids of chain length greater than C18: maximum 4.0 per cent.<\/p>\n<h3>Total ash (2.4.16)<\/h3>\n<p>Maximum 0.1 per cent, determined on 2.00 g.<\/p>\n<h2>STORAGE<\/h2>\n<p>In an airtight, well-filled container, protected from light.<\/p>\n<h2>LABELLING<\/h2>\n<p>The label states the origin of oleic acid (animal or vegetable).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>(Ph. Eur. monograph 0799) 112-80-1 Action and use Excipient. DEFINITION (Z)-Octadec-9-enoic acid (C18H34O2; Mr 282.5), together with varying amounts of saturated and other unsaturated fatty acids. A suitable antioxidant may be added. Content 65.0 per cent to 88.0 per cent of C18H34O2. CHARACTERS Appearance Clear, yellowish or brownish, oily liquid. Solubility Practically insoluble in water,&#8230;<\/p>\n","protected":false},"author":4,"featured_media":25968,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[174],"tags":[],"class_list":["post-25966","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicinal-substances"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/25966","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=25966"}],"version-history":[{"count":2,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/25966\/revisions"}],"predecessor-version":[{"id":25970,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/25966\/revisions\/25970"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/25968"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=25966"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=25966"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=25966"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}