BP 2025 (Ph. Eur. 11.6 update)<\/p>\n
Action and use<\/strong><\/p>\n Non-ionic surfactant.<\/p>\n Mixture of ethers of mixed macrogols with linear fatty alcohols, mainly oleyl alcohol. It contains a variable quantity of free oleyl alcohol and it may contain free macrogols. The number of moles of ethylene oxide reacted per mole of oleyl alcohol is 2 to 20 (nominal value). A suitable antioxidant may be added.<\/p>\n \u2014 Macrogol oleyl ether with 2 to 5 units of ethylene oxide per molecule.<\/p>\n Appearance<\/strong><\/p>\n Yellow liquid.<\/p>\n Solubility<\/strong><\/p>\n Practically insoluble in water, soluble in ethanol (96 per cent), practically insoluble in light petroleum.<\/p>\n \u2014 Macrogol oleyl ether with 10 to 20 units of ethylene oxide per molecule.<\/p>\n Appearance<\/strong><\/p>\n Yellowish-white waxy mass.<\/p>\n Solubility<\/strong><\/p>\n Dispersible or soluble in water, soluble in ethanol (96 per cent), practically insoluble in light petroleum.<\/p>\n A. Hydroxyl value (see Tests). Appearance of solution<\/strong><\/p>\n The solution is not more intensely coloured than reference solution BY5 (2.2.2, Method II).<\/p>\n Dissolve 5.0 g in alcohol R and dilute to 50 mL with the same solvent.<\/p>\n Alkalinity<\/strong><\/p>\n Dissolve 2.0 g in a hot mixture of 10 mL of water R and 10 mL of alcohol R. Add 0.1 mL of bromothymol blue solution R1. Not more than 0.5 mL of 0.1 M hydrochloric acid is required to change the colour of the indicator to yellow.<\/p>\n Acid value (2.5.1)<\/strong><\/p>\n Maximum 1.0, determined on 5.0 g.<\/p>\n Hydroxyl value (2.5.3, Method A)<\/strong><\/p>\n See Table 1125.-1.<\/p>\n Iodine value (2.5.4)<\/strong><\/p>\n See Table 1125.-1.<\/p>\n Table 1125.-1<\/p>\n * This broad range is needed since 2 different grades of oleyl alcohol may be used for the synthesis. The iodine value does not differ by more than 5 units from the nominal iodine value and is within the limits stated in the table.<\/p>\n Peroxide value (2.5.5)<\/strong><\/p>\n Maximum 10.0.<\/p>\n Saponification value (2.5.6)<\/strong><\/p>\n Maximum 3.0.<\/p>\n Ethylene oxide and dioxan (2.4.25)<\/strong><\/p>\n Maximum 1 ppm of ethylene oxide and 10 ppm of dioxan.<\/p>\n Water (2.5.12)<\/strong><\/p>\n Maximum 3.0 per cent, determined on 2.00 g.<\/p>\n Total ash (2.4.16)<\/strong><\/p>\n Maximum 0.2 per cent, determined on 2.0 g.<\/p>\n In an airtight container, protected from light.<\/p>\n The label states: BP 2025 (Ph. Eur. 11.6 update) Action and use Non-ionic surfactant. DEFINITION Mixture of ethers of mixed macrogols with linear fatty alcohols, mainly oleyl alcohol. It contains a variable quantity of free oleyl alcohol and it may contain free macrogols. The number of moles of ethylene oxide reacted per mole of oleyl alcohol is 2…<\/p>\n","protected":false},"author":5,"featured_media":21738,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[174],"tags":[],"class_list":["post-21704","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicinal-substances"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/21704","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=21704"}],"version-history":[{"count":2,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/21704\/revisions"}],"predecessor-version":[{"id":21742,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/21704\/revisions\/21742"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/21738"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=21704"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=21704"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=21704"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}DEFINITION<\/h2>\n
CHARACTERS<\/h2>\n
IDENTIFICATION<\/h2>\n
\nB. Iodine value (see Tests).
\nC. Saponification value (see Tests).
\nD. Dissolve or disperse 0.1 g in 5 mL of alcohol R, add 2 mL of water R, 10 mL of dilute hydrochloric acid R, 10 mL of barium chloride solution R1 and 10 mL of a 100 g\/L solution of phosphomolybdic acid R. A precipitate is formed.<\/p>\nTESTS<\/h2>\n
\n\n
\n Ethylene oxide unitsn per molecule
\n(nominal value)<\/td>\nHydroxyl value<\/td>\n Iodine value<\/td>\n<\/tr>\n \n 2<\/td>\n 158 – 178<\/td>\n 48 – 74*<\/td>\n<\/tr>\n \n 5<\/td>\n 110 – 125<\/td>\n 48 – 56<\/td>\n<\/tr>\n \n 10<\/td>\n 75 – 95<\/td>\n 24 – 38<\/td>\n<\/tr>\n \n 20<\/td>\n 40 – 65<\/td>\n 14 – 24<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n STORAGE<\/h2>\n
LABELLING<\/h2>\n
\n\u2014 the number of moles of ethylene oxide reacted per mole of oleyl alcohol (nominal value),
\n\u2014 the nominal iodine value for the type with 2 units of ethylene oxide per molecule.<\/p>\n","protected":false},"excerpt":{"rendered":"