{"id":21456,"date":"2025-10-28T15:36:22","date_gmt":"2025-10-28T08:36:22","guid":{"rendered":"https:\/\/nhathuocngocanh.com\/bp\/?p=21456"},"modified":"2025-10-28T15:36:22","modified_gmt":"2025-10-28T08:36:22","slug":"lactic-acid-pessaries","status":"publish","type":"post","link":"https:\/\/nhathuocngocanh.com\/bp\/lactic-acid-pessaries\/","title":{"rendered":"Lactic Acid Pessaries"},"content":{"rendered":"<p>Edition: BP 2025 (Ph. Eur. 11.6 update)<\/p>\n<h2>DEFINITION<\/h2>\n<p>Lactic Acid Pessaries are moulded pessaries containing Lactic Acid in a suitable basis.<\/p>\n<p>The pessaries comply with the requirements stated under Vaginal Preparations and with the following requirements.<\/p>\n<p><strong>Content of lactic acid, C<sub>3<\/sub>H<sub>6<\/sub>O<sub>3<\/sub><\/strong>:<br \/>\n95.0 to 105.0% of the stated amount.<\/p>\n<h2>ASSAY<\/h2>\n<p>Weigh five pessaries, melt together by warming and allow to cool, stirring continuously.<\/p>\n<p>Dissolve a quantity of the mass containing 1 g of Lactic Acid in 50 mL of water.<\/p>\n<p>Add 50 mL of 0.5M sodium hydroxide VS, boil gently for 5 minutes, cool and titrate the excess of alkali with 0.5M hydrochloric acid VS using phenolphthalein solution R1 as indicator.<\/p>\n<p>Each mL of 0.5M sodium hydroxide VS is equivalent to 45.04 mg of C<sub>3<\/sub>H<sub>6<\/sub>O<sub>3<\/sub>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Edition: BP 2025 (Ph. Eur. 11.6 update) DEFINITION Lactic Acid Pessaries are moulded pessaries containing Lactic Acid in a suitable basis. The pessaries comply with the requirements stated under Vaginal Preparations and with the following requirements. Content of lactic acid, C3H6O3: 95.0 to 105.0% of the stated amount. ASSAY Weigh five pessaries, melt together by&#8230;<\/p>\n","protected":false},"author":5,"featured_media":21457,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[175],"tags":[],"class_list":["post-21456","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-formulated-preparations-specific-monographs"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/21456","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=21456"}],"version-history":[{"count":2,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/21456\/revisions"}],"predecessor-version":[{"id":21460,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/21456\/revisions\/21460"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/21457"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=21456"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=21456"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=21456"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}