{"id":20721,"date":"2025-10-27T16:10:19","date_gmt":"2025-10-27T09:10:19","guid":{"rendered":"https:\/\/nhathuocngocanh.com\/bp\/?p=20721"},"modified":"2025-11-15T17:13:45","modified_gmt":"2025-11-15T10:13:45","slug":"salicylic-acid-cream","status":"publish","type":"post","link":"https:\/\/nhathuocngocanh.com\/bp\/salicylic-acid-cream\/","title":{"rendered":"Salicylic Acid Cream"},"content":{"rendered":"<p>NOTE: This monograph has been developed to cover unlicensed formulations.<\/p>\n<p><strong>Action and use<\/strong><\/p>\n<p>Keratolytic.<\/p>\n<h2>DEFINITION<\/h2>\n<p>Salicylic Acid Cream contains Salicylic Acid in Aqueous Cream.<\/p>\n<p>The cream complies with the requirements stated under Topical Semi-solid Preparations and with the following requirements. Where appropriate, the cream also complies with the requirements stated under Unlicensed Medicines.<\/p>\n<p><strong>Content of salicylic acid, C<sub>7<\/sub>H<sub>6<\/sub>O<sub>3<\/sub><\/strong><\/p>\n<p>95.0 to 105.0% of the stated amount.<\/p>\n<h2>IDENTIFICATION<\/h2>\n<p>Shake 1 g with 10 mL of water, filter and add to the filtrate iron(III) chloride solution R1; an intense reddish violet colour is produced which persists on the addition of 6M acetic acid. Add 2M hydrochloric acid; the colour disappears and a white, crystalline precipitate is produced.<\/p>\n<h2>ASSAY<\/h2>\n<p>Dissolve a quantity of the cream containing 0.25 g of Salicylic Acid in a mixture of 20 mL of ethanol (96%), previously neutralised to phenol red solution, and 20 mL of ether and titrate with 0.1M sodium hydroxide VS using phenol red solution as indicator. Each mL of 0.1M sodium hydroxide VS is equivalent to 13.81 mg of C<sub>7<\/sub>H<sub>6<\/sub>O<sub>3<\/sub><\/p>\n","protected":false},"excerpt":{"rendered":"<p>NOTE: This monograph has been developed to cover unlicensed formulations. Action and use Keratolytic. DEFINITION Salicylic Acid Cream contains Salicylic Acid in Aqueous Cream. The cream complies with the requirements stated under Topical Semi-solid Preparations and with the following requirements. Where appropriate, the cream also complies with the requirements stated under Unlicensed Medicines. Content of&#8230;<\/p>\n","protected":false},"author":4,"featured_media":20725,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[175],"tags":[],"class_list":["post-20721","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-formulated-preparations-specific-monographs"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/20721","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=20721"}],"version-history":[{"count":2,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/20721\/revisions"}],"predecessor-version":[{"id":20727,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/20721\/revisions\/20727"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/20725"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=20721"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=20721"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=20721"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}