Edition: BP 2025 (Ph. Eur. 11.6 update)<\/p>\n
Sodium Bicarbonate Infusion is a sterile solution containing Sodium Bicarbonate. It is supplied as a ready-to-use solution.<\/p>\n
The infusion complies with the requirements stated under Parenteral Preparations and with the following requirements.<\/em><\/p>\n Content of sodium bicarbonate, NaHCO3<\/sub><\/strong><\/p>\n 94.0 to 106.0% of the stated amount.<\/p>\n A. The residue on evaporation, when moistened with hydrochloric acid and introduced on a platinum wire into a flame, imparts a yellow colour to the flame.<\/p>\n B. Yields reaction A characteristic of sodium salts and the reactions characteristic of bicarbonates, Appendix VI.<\/p>\n Bacterial endotoxins<\/strong><\/p>\n Carry out the test for bacterial endotoxins, Appendix XIV C. The endotoxin limit concentration is less than 1.7 IU per mL of Sodium Bicarbonate Infusion.<\/p>\n Titrate a volume containing 1 g of Sodium Bicarbonate with 0.5M hydrochloric acid VS using methyl orange solution as indicator. Each mL of 0.5M hydrochloric acid VS is equivalent to 42.00 mg of NaHCO3<\/sub>.<\/p>\n Containers that have previously been subjected to heating in an autoclave should not be re-used to keep Sodium Bicarbonate Infusion.<\/p>\n The strength is stated as the percentage w\/v of Sodium Bicarbonate.<\/p>\n The label states (1) that containers containing visible particles must not be used; (2) the approximate concentrations, in millimoles per litre, of the sodium ions and the bicarbonate ions.<\/p>\n For a preparation containing 1.4% w\/v of Sodium Bicarbonate the concentration of each ion is stated as 167 millimoles per litre.<\/p>\n","protected":false},"excerpt":{"rendered":" Edition: BP 2025 (Ph. Eur. 11.6 update) DEFINITION Sodium Bicarbonate Infusion is a sterile solution containing Sodium Bicarbonate. It is supplied as a ready-to-use solution. The infusion complies with the requirements stated under Parenteral Preparations and with the following requirements. Content of sodium bicarbonate, NaHCO3 94.0 to 106.0% of the stated amount. IDENTIFICATION A. The…<\/p>\n","protected":false},"author":5,"featured_media":20690,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[175],"tags":[],"class_list":["post-20689","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-formulated-preparations-specific-monographs"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/20689","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=20689"}],"version-history":[{"count":2,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/20689\/revisions"}],"predecessor-version":[{"id":20738,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/20689\/revisions\/20738"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/20690"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=20689"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=20689"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=20689"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}IDENTIFICATION<\/h2>\n
TESTS<\/h2>\n
ASSAY<\/h2>\n
STORAGE<\/h2>\n
LABELLING<\/h2>\n