Edition: BP 2025 (Ph. Eur. 11.6 update)<\/p>\n
Action and use<\/strong><\/p>\n Hydrating agent; adjunctive therapy for use with platinum based cytotoxics.<\/p>\n Magnesium Sulfate, Potassium Chloride and Sodium Chloride Infusion is a sterile, isotonic solution containing Magnesium Sulfate Heptahydrate, Potassium Chloride and Sodium Chloride. It is supplied as a ready-to-use solution.<\/p>\n The infusion complies with the requirements stated under Parenteral Preparations and with the following requirements. Where appropriate, the infusion also complies with the requirements stated under Unlicensed Medicines.<\/em><\/p>\n Content of magnesium, Mg<\/strong><\/p>\n 95.0 to 105.0% of the stated amount.<\/p>\n Content of potassium, K<\/strong><\/p>\n 95.0 to 105.0% of the stated amount.<\/p>\n Content of sodium, Na<\/strong><\/p>\n 95.0 to 105.0% of the stated amount.<\/p>\n A. Yields reaction B characteristic of magnesium salts and the reactions characteristic of potassium salts and of sodium salts, Appendix VI.<\/p>\n B. Yields reaction A characteristic of chlorides and reaction A characteristic of sulfates, Appendix VI.<\/p>\n Acidity<\/strong><\/p>\n pH, 5.0 to 6.0, Appendix V L.<\/p>\n Transfer 100 mL into a 500 mL conical flask and carry out the complexometric titration of magnesium, Appendix VIII D, beginning at the words \u2018and dilute to 300 mL with water\u2026\u2019. Each mL of 0.1M disodium edetate VS is equivalent to 0.1 mmol (2.431 mg) of Mg.<\/p>\n Dilute appropriately with water and determine by atomic emission spectrophotometry, Appendix II D, measuring at 767 nm and using potassium standard solution (600 ppm K), suitably diluted with water, to prepare the standard solutions.<\/p>\n Dilute appropriately with water and determine by atomic emission spectrophotometry, Appendix II D, measuring at 589 nm and using sodium standard solution (200 ppm Na), suitably diluted with water, to prepare the standard solutions.<\/p>\n Magnesium Sulfate, Potassium Chloride and Sodium Chloride Infusion should be protected from light.<\/p>\n The strength is stated as the approximate concentration, in millimoles per litre, of Magnesium Sulfate and of Potassium Chloride and as the percentage w\/v of Sodium Chloride.<\/p>\n","protected":false},"excerpt":{"rendered":" Edition: BP 2025 (Ph. Eur. 11.6 update) Action and use Hydrating agent; adjunctive therapy for use with platinum based cytotoxics. DEFINITION Magnesium Sulfate, Potassium Chloride and Sodium Chloride Infusion is a sterile, isotonic solution containing Magnesium Sulfate Heptahydrate, Potassium Chloride and Sodium Chloride. It is supplied as a ready-to-use solution. The infusion complies with the…<\/p>\n","protected":false},"author":5,"featured_media":17633,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[175],"tags":[],"class_list":["post-17632","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-formulated-preparations-specific-monographs"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/17632","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=17632"}],"version-history":[{"count":2,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/17632\/revisions"}],"predecessor-version":[{"id":17647,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/17632\/revisions\/17647"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/17633"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=17632"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=17632"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=17632"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}DEFINITION<\/h2>\n
IDENTIFICATION<\/h2>\n
TESTS<\/h2>\n
ASSAY<\/h2>\n
For magnesium<\/h3>\n
For potassium<\/h3>\n
For sodium<\/h3>\n
STORAGE<\/h2>\n
LABELLING<\/h2>\n