{"id":16143,"date":"2025-10-18T17:17:20","date_gmt":"2025-10-18T10:17:20","guid":{"rendered":"https:\/\/nhathuocngocanh.com\/bp\/?p=16143"},"modified":"2025-10-18T17:17:20","modified_gmt":"2025-10-18T10:17:20","slug":"glycerol-eye-drops","status":"publish","type":"post","link":"https:\/\/nhathuocngocanh.com\/bp\/glycerol-eye-drops\/","title":{"rendered":"Glycerol Eye Drops"},"content":{"rendered":"<p>(Ph. Eur. 11.6 update)<\/p>\n<h2>DEFINITION<\/h2>\n<p>Glycerol Eye Drops are a sterile solution of Glycerol in Purified Water.<\/p>\n<p>The eye drops comply with the requirements stated under Eye Preparations and with the following requirements.<\/p>\n<p><strong>Content of glycerol, C<sub>3<\/sub>H<sub>8<\/sub>O<sub>3<\/sub><\/strong><\/p>\n<p>95.0 to 105.0% of the stated amount.<\/p>\n<h2>IDENTIFICATION<\/h2>\n<p>Mix 1 mL of the eye drops with 0.5 mL of nitric acid and superimpose 0.5 mL of potassium dichromate solution. A blue ring develops at the interface of the liquids, which does not diffuse into the lower layer within 10 minutes.<\/p>\n<h2>TESTS<\/h2>\n<p><strong>Acidity or alkalinity<\/strong><\/p>\n<p>pH, 4.5 to 7.5, Appendix V L.<\/p>\n<h2>ASSAY<\/h2>\n<p>Dilute a suitable volume of the eye drops with sufficient water to produce a solution containing 3% w\/v of Glycerol. To 5 mL add 150 mL of water and neutralise with 0.1M sodium hydroxide VS, using bromocresol purple solution as indicator. Add 1.6 g of sodium periodate and allow to stand protected from light for 15 minutes. Add 3 mL of propan-1,2-diol, shake, allow to stand protected from light for 5 minutes and titrate with 0.1M sodium hydroxide VS. Each mL of 0.1M sodium hydroxide VS is equivalent to 9.21 mg of C<sub>3<\/sub>H<sub>8<\/sub>O<sub>3<\/sub><\/p>\n<h2>STORAGE<\/h2>\n<p>Glycerol Eye Drops should be protected from light.<\/p>\n<p><strong>Strengths available<\/strong><\/p>\n<p>Eye Drops containing 10, 20, 30 and 50% w\/v of glycerol are available.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>(Ph. Eur. 11.6 update) DEFINITION Glycerol Eye Drops are a sterile solution of Glycerol in Purified Water. The eye drops comply with the requirements stated under Eye Preparations and with the following requirements. Content of glycerol, C3H8O3 95.0 to 105.0% of the stated amount. IDENTIFICATION Mix 1 mL of the eye drops with 0.5 mL&#8230;<\/p>\n","protected":false},"author":4,"featured_media":16144,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[175],"tags":[],"class_list":["post-16143","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-formulated-preparations-specific-monographs"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/16143","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=16143"}],"version-history":[{"count":1,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/16143\/revisions"}],"predecessor-version":[{"id":16153,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/16143\/revisions\/16153"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/16144"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=16143"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=16143"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=16143"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}