Dilute Hydrogen Peroxide Solution<\/p>\n
(Ph. Eur. monograph 0395)<\/em><\/p>\n Action and use<\/strong><\/p>\n Antiseptic; deodorant.<\/p>\n When hydrogen peroxide is prescribed or demanded, Hydrogen Peroxide Solution (6 per cent) shall be dispensed or supplied.<\/p>\n 2.5 per cent m\/m to 3.5 per cent m\/m of H2<\/sub>O2<\/sub> (Mr 34.01).<\/p>\n 1 volume of hydrogen peroxide solution (3 per cent) corresponds to about 10 times its volume of oxygen. A suitable stabiliser may be added.<\/p>\n Colourless, clear liquid.<\/p>\n A. To 2 mL, add 0.2 mL of dilute sulfuric acid R and 0.2 mL of 0.02 M potassium permanganate. The solution becomes colourless or slightly pink within 2 min.<\/p>\n B. To 1 mL, add 0.1 mL of dilute hydrochloric acid R and 0.1 mL of potassium iodide solution R. A brown colour appears.<\/p>\n Black particles may be formed.<\/p>\n C. It complies with the requirement for the content of H2O2.<\/p>\n Hydrogen Peroxide Solution (3 per cent)<\/p>\n To 10 mL, add 20 mL of water R and 0.25 mL of methyl red solution R. Not less than 0.05 mL and not more than 1.0 mL of 0.1 M sodium hydroxide is required to change the colour of the indicator.<\/p>\n Maximum 250 ppm.<\/p>\n Shake 20 mL with 10 mL of chloroform R and then with 2 quantities, each of 5 mL, of chloroform R. Evaporate the combined chloroform layers under reduced pressure at a temperature not exceeding 25 \u00b0C and dry in a desiccator. The residue weighs a maximum of 5 mg.<\/p>\n Maximum 2 g\/L.<\/p>\n Allow 10 mL to stand in a platinum dish until all effervescence has ceased. Evaporate to dryness on a water-bath and dry at 100-105 \u00b0C. The residue weighs a maximum of 20 mg.<\/p>\n Dilute 10.0 g to 100.0 mL with water R. To 10.0 mL of this solution add 20 mL of dilute sulfuric acid R. Titrate with 0.02 M potassium permanganate until a pink colour is obtained.<\/p>\n 1 mL of 0.02 M potassium permanganate is equivalent to 1.701 mg of H2<\/sub>O2<\/sub> or 0.56 mL of oxygen.<\/p>\n Protected from light, and if the solution does not contain a stabiliser, at a temperature below 15 \u00b0C.<\/p>\n If the solution contains a stabiliser, the label states that the contents are stabilised. The competent authority may require that the name of the stabiliser be stated on the label.<\/p>\n It decomposes in contact with oxidisable organic matter and with certain metals and if allowed to become alkaline.<\/p>\n","protected":false},"excerpt":{"rendered":" Dilute Hydrogen Peroxide Solution (Ph. Eur. monograph 0395) Action and use Antiseptic; deodorant. When hydrogen peroxide is prescribed or demanded, Hydrogen Peroxide Solution (6 per cent) shall be dispensed or supplied. DEFINITION Content 2.5 per cent m\/m to 3.5 per cent m\/m of H2O2 (Mr 34.01). 1 volume of hydrogen peroxide solution (3 per cent)…<\/p>\n","protected":false},"author":4,"featured_media":16012,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[174],"tags":[],"class_list":["post-15998","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicinal-substances"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/15998","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=15998"}],"version-history":[{"count":2,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/15998\/revisions"}],"predecessor-version":[{"id":16014,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/15998\/revisions\/16014"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/16012"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=15998"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=15998"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=15998"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}DEFINITION<\/h2>\n
Content<\/h3>\n
CHARACTERS<\/h2>\n
Appearance<\/h3>\n
IDENTIFICATION<\/h2>\n
TESTS<\/h2>\n
Acidity<\/h3>\n
Organic stabilisers<\/h3>\n
Non-volatile residue<\/h3>\n
ASSAY<\/h2>\n
STORAGE<\/h2>\n
LABELLING<\/h2>\n
CAUTION<\/h2>\n