(Ph. Eur. monograph 0031)<\/p>\n
I2<\/sub>\u00a0 \u00a0 \u00a0 \u00a0253.8 7553-56-2<\/p>\n Action and use<\/strong><\/p>\n Antiseptic; antithyroid.<\/p>\n Preparations<\/strong><\/p>\n Alcoholic Iodine Solution<\/p>\n Aqueous Iodine Oral Solution<\/p>\n Povidone-Iodine Eye Drops<\/p>\n Povidone-Iodine Mouthwash<\/p>\n Povidone-Iodine Solution<\/p>\n 99.5 per cent to 100.5 per cent of I.<\/p>\n Greyish-violet, brittle plates or fine crystals with a metallic sheen.<\/p>\n Very slightly soluble in water, very soluble in concentrated solutions of iodides, soluble in ethanol (96 per cent), slightly soluble in glycerol.<\/p>\n It volatilises slowly at room temperature.<\/p>\n A. Heat a few fragments in a test-tube. Violet vapour is evolved and a bluish-black crystalline sublimate is formed.<\/p>\n B. To a saturated solution add starch solution R. A blue colour is produced. Heat until decolourised. On cooling, the colour reappears.<\/p>\n Triturate 3.0 g with 20 mL of water R, filter, wash the filter with water R and dilute the filtrate to 30 mL with the same solvent. To the solution add 1 g of zinc powder R. When the solution is decolourised, filter, wash the filter with water R and dilute to 40 mL with the same solvent.<\/p>\n Maximum 250 ppm.<\/p>\n To 10 mL of solution S add 3 mL of ammonia R and 6 mL of silver nitrate solution R2. Filter, wash the filter with water R and dilute the filtrate to 20 mL with the same solvent. To 10 mL of the solution add 1.5 mL of nitric acid R. After 1 min, any opalescence in the solution is not more intense than that in a standard prepared at the same time by mixing 10.75 mL of water R, 0.25 mL of 0.01 M hydrochloric acid, 0.2 mL of dilute nitric acid R and 0.3 mL of silver nitrate solution R2.<\/p>\n Maximum 0.1 per cent.<\/p>\n Heat 1.00 g in a porcelain dish on a water-bath until the iodine has volatilised. Dry the residue at 100-105 \u00b0C. The residue weighs a maximum of 1 mg.<\/p>\n Introduce 0.200 g into a flask containing 1 g of potassium iodide R and 2 mL of water R and add 1 mL of dilute acetic acid R. When dissolution is complete, add 50 mL of water R and titrate with 0.1 M sodium thiosulfate, using starch solution R as indicator.<\/p>\n 1 mL of 0.1 M sodium thiosulfate is equivalent to 12.69 mg of I.<\/p>\n","protected":false},"excerpt":{"rendered":" (Ph. Eur. monograph 0031) I2\u00a0 \u00a0 \u00a0 \u00a0253.8 7553-56-2 Action and use Antiseptic; antithyroid. Preparations Alcoholic Iodine Solution Aqueous Iodine Oral Solution Povidone-Iodine Eye Drops Povidone-Iodine Mouthwash Povidone-Iodine Solution DEFINITION Content 99.5 per cent to 100.5 per cent of I. CHARACTERS Appearance Greyish-violet, brittle plates or fine crystals with a metallic sheen. Solubility Very slightly…<\/p>\n","protected":false},"author":2,"featured_media":15676,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-15673","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-volumes-1-2"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/15673","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=15673"}],"version-history":[{"count":2,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/15673\/revisions"}],"predecessor-version":[{"id":15678,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/15673\/revisions\/15678"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/15676"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=15673"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=15673"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=15673"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}DEFINITION<\/h2>\n
Content<\/h3>\n
CHARACTERS<\/h2>\n
Appearance<\/h3>\n
Solubility<\/h3>\n
IDENTIFICATION<\/h2>\n
TESTS<\/h2>\n
Solution S<\/h3>\n
Bromides and chlorides<\/h3>\n
Non-volatile substances<\/h3>\n
ASSAY<\/h2>\n