DEFINITION<\/h2>\n
Mixture of 1,3-dioxan-5-ol and (1,3-dioxolan-4-yl)methanol.<\/p>\n
CHARACTERS<\/h2>\nAppearance<\/h3>\n
Clear, colourless liquid.<\/p>\n
Solubility<\/h3>\n
Miscible with water and with ethanol (96 per cent).<\/p>\n
IDENTIFICATION<\/h2>\n
A. Relative density (see Tests).<\/p>\n
B. Refractive index (see Tests).<\/p>\n
C. Infrared absorption spectrophotometry (2.2.24).<\/p>\n
Comparison glycerol formal CRS.<\/p>\n
TESTS<\/h2>\nAppearance<\/h3>\n
The substance to be examined is clear (2.2.1) and colourless (2.2.2, Method II).<\/p>\n
pH (2.2.3)<\/h3>\n
4.0 to 6.5.<\/p>\n
Dilute 1 mL to 10 mL with carbon dioxide-free water R.<\/p>\n
Relative density (2.2.5)<\/h3>\n
1.210 to 1.220.<\/p>\n
Refractive index (2.2.6)<\/h3>\n
1.445 to 1.455.<\/p>\n
Peroxide value (2.5.5)<\/h3>\n
Maximum 15.<\/p>\n
Formaldehyde<\/h3>\n
Maximum 200 ppm.<\/p>\n
Dilute 0.250 g to 10 mL with water R. Add 2.0 mL of acetylacetone reagent R2, mix and heat on a water-bath at 60 \u00b0C for 20 min. Cool and dilute to 20.0 mL with water R. The absorbance (2.2.25) of the solution measured at 412 nm is not greater than that of a standard prepared at the same time and in the same manner using 5.0 mL of a dilution of formaldehyde solution R containing 10 \u03bcg of formaldehyde (CH2O) per millilitre.<\/p>\n
Water (2.5.12)<\/h3>\n
Maximum 0.5 per cent, determined on 5.000 g.<\/p>\n
IMPURITIES<\/h2>\n
Specified impurities A.<\/p>\n
![\"Glycerol](\"https:\/\/nhathuocngocanh.com\/bp\/wp-content\/uploads\/2025\/10\/1-155-300x163.jpg\")
<\/p>\n
A. formaldehyde.<\/p>\n
STORAGE<\/h2>\n
Under nitrogen, in an airtight container.<\/p>\n","protected":false},"excerpt":{"rendered":"
(Ph. Eur. monograph 1671) C4H8O3\u00a0 \u00a0104.1 DEFINITION Mixture of 1,3-dioxan-5-ol and (1,3-dioxolan-4-yl)methanol. CHARACTERS Appearance Clear, colourless liquid. Solubility Miscible with water and with ethanol (96 per cent). IDENTIFICATION A. Relative density (see Tests). B. Refractive index (see Tests). C. Infrared absorption spectrophotometry (2.2.24). Comparison glycerol formal CRS. TESTS Appearance The substance to be examined is…<\/p>\n","protected":false},"author":3,"featured_media":13463,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[174],"tags":[],"class_list":["post-13329","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicinal-substances"],"acf":[],"_links":{"self":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/13329","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/comments?post=13329"}],"version-history":[{"count":4,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/13329\/revisions"}],"predecessor-version":[{"id":13465,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/posts\/13329\/revisions\/13465"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media\/13463"}],"wp:attachment":[{"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/media?parent=13329"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/categories?post=13329"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhathuocngocanh.com\/bp\/wp-json\/wp\/v2\/tags?post=13329"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}